Through decades of work at Columbia University, Duke University, the National University of Singapore, where he founded the first ever Mechanobiology Institute (MBI), and beyond, Mike discovered that mechanical cues — not just genes and chemicals — play a vital role in regulating cell function. His research showed that low-frequency mechanical stimulation could awaken the regenerative potential of senescent cells, offering a new paradigm for how we understand aging and disease.

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In the final years of his life, Mike began translating this science into a therapeutic reality. Alongside a small group of collaborators, he helped develop early prototypes of ultrasound-based devices that could rejuvenate tissues in vivo. What began as a bold scientific idea soon showed promise in animal studies, with aged mice after treatment exhibiting signs of cellular renewal, improved function, and extended vitality.

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Mechanobiologics, Inc. was formed to continue this mission: to transform breakthrough discoveries in mechanobiology into real-world interventions that extend healthspan, delay disease, and restore the body’s natural capacity to heal.

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Although Mike is no longer with us, his spirit guides every step we take. We remain deeply committed to the values he embodied: scientific curiosity, rigor, humility, and hope. His legacy lives on in our work — not only in honoring what he discovered, but in realizing what he envisioned.